Omega-3s Reduce Symptoms of Anxiety by 20%

A soon to be published study has shown Omega-3’s to also have benefit in the treatment of anxiety. The great thing about the study is that it was done in humans and with a very reasonable dose of 2.5 grams per day.

The study entitled Omega-3 supplementation lowers inflammation and anxiety in medical students: A randomized controlled trial is the first study to demonstrate in humans that Omega-3’s may have anxiolytic benefits.

Study Details

• Observational studies have linked lower omega-3’s and polyunsaturated fatty acids levels with inflammation and depression, but studies had been mixed on the correlation. The study set out to determine if Omega-3’s decrease proinflammatory cytokine production and depressive and anxiety symptoms in healthy young adults,

• Study was designed as a placebo-controlled, double-blind 12-week RCT compared n-3 supplementation with placebo.
• The participants, 68 medical students, provided serial blood samples during lower-stress periods as well as on days before an exam.
• The students received either 2.5 g/d, 2085 mg EPA and 348 mg DHA or placebo capsules that mirrored the proportions of fatty acids in the typical American diet.
• Compared to controls, those students who received Omega-3’s showed a 14% decrease in lipopolysaccharide (LPS) stimulated interleukin 6 (IL-6) production and a 20% reduction in anxiety
The data suggests that Omega-3 supplementation can reduce inflammation and anxiety even among healthy young adults. This is not only great news for people who may want to alleviate some anxiety, but also for those who use Omega-3 ‘s already for health promoting reasons; they get this additional side-benefit as well.

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